Similar words: upon, coupon, act upon, set upon, put upon, thereupon, fall upon, run upon. Meaning: adj. being up to particular standard or level especially in being up to date in knowledge.
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181. A good book is the precious life-blood of a master spirit, embalmed and treasured up on purpose to a life beyond life. John Milton 
182. We are never defeated unless we give up on God. Ronald Reagan
183. We don't give up on hope. We hope, to not give up. Anthony Liccione
More similar words: upon, coupon, act upon, set upon, put upon, thereupon, fall upon, run upon, come upon, frown upon, pick up on, bear upon, look upon, gang up on, whereupon, enter upon, check up on, hinge upon, chance upon, impress upon, depend upon, coupon bond, stumble upon, once upon a time, make up one's mind, stupor, made up of, cup of tea, be made up of, avoirdupois.